Anti-TDG Antibody (A320181)

Anti-TDG Antibody

Rabbit polyclonal antibody to TDG.

This antibody recognises G/T mismatch-specific thymine DNA glycosylase.TDG is a member of the TDG/mug DNA glycosylase family and predominantly removes thymine residues from sites where G/T mismatches have occurred. TDG can also remove thymine from C/T and T/T mispairings and uracil and 5-bromouracil from mispairings with guanine. TDG may also play a role in 5-methylcytosine demethylation in mammalian cells.

WB: 1:500 - 1:1500

Mouse

A full-length recombinant protein corresponding to mouse TDG.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Mouse TDG antibody recognizes G/T mismatch-specific thymine DNA glycosylase.TDG is a member of the TDG/mug DNA glycosylase family and predominantly removes thymine residues from sites where G/T mismatches have occurred. TDG can also remove thymine from C/T and T/T mispairings and uracil and 5-bromouracil from mispairings with guanine (Gallinari and Jiricny, 1996). TDG may also play a role in 5-methylcytosine demethylation in mammalian cells (Zhang et al. 2012).

G/T mismatch-specific thymine DNA glycosylase, hTDG, Thymine-DNA glycosylase