Anti-TdT Antibody [HT-1 + HT-4 + HT-8 + HT-9] (FITC) (A280659)

Anti-TdT Antibody [HT-1 + HT-4 + HT-8 + HT-9] (FITC)

Mouse oligoclonal [HT-1 + HT-4 + HT-8 + HT-9] antibody to TdT (FITC).

This antibody recognises human terminal deoxynucleotidyl transferase (TdT). TdT is a DNA polymerase responsible for the catalysis of non-reversible addition of deoxynucleotides to the 3' end hydroxy groups of DNA. TdT levels are enhanced in all forms of acute lymphoblastic leukaemia (ALL) and in a significant number of chronic lymphoblastic leukaemia cases (CML). TdT is not expressed in the majority of myeloid leukaemias, non-Hodgkins lymphomas or mature lymphoid leukaemias.

FC 1: Neat, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Oligoclonal

HT-1 + HT-4 + HT-8 + HT-9

50 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human TdT antibody panel is a mixture of 4 monoclonal antibodies specific for human terminal deoxynucleotidyl transferase (TdT). TdT is a DNA polymerase responsible for the catalysis of non-reversible addition of deoxynucleotides to the 3' end hydroxy groups of DNA. TdT levels are enhanced in all forms of acute lymphoblastic leukaemia (ALL) and in a significant number of chronic lymphoblastic leukaemia cases (CML). TdT is not expressed in the majority of myeloid leukaemias, non-Hodgkins lymphomas or mature lymphoid leukaemias.

DNA nucleotidylexotransferase, DNTT, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase

This product is for research use only. It is not intended for diagnostic or therapeutic use.