This antibody recognises mouse toll-interleukin 1 receptor domain containing adaptor protein, also known as TIRAP, MyD88 adapter-like protein or Mal. TIRAP is one of a family of TIR domain-containing proteins which serve as adaptor proteins for the Toll-like receptors during the innate immune response. TIRAP is reported to participate in the MyD88-dependent signaling pathways shared by TLR2 and TLR4.
Applications
WB, IHC-P
Dilutions
WB: 0.5 µg/ml - 2 µg/ml
Reactivity
Mouse, Human, Rat
Immunogen
Synthetic peptide corresponding to a region within the C-Terminus of mouse TIRAP.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti TIRAP antibody recognizes mouse toll-interleukin 1 receptor domain containing adaptor protein, also known as TIRAP, MyD88 adapter-like protein or Mal. TIRAP is one of a family of TIR domain-containing proteins which serve as adaptor proteins for the Toll-like receptors during the innate immune response. TIRAP is reported to participate in the MyD88-dependent signaling pathways shared by TLR2 and TLR4.
Synonyms
Adaptor protein Wyatt, MAL, MyD88 adapter-like protein, MyD88-2, TIR domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein