Anti-TLR2 Antibody [11G7] (PE) (A278976)

Anti-TLR2 Antibody [11G7] (PE)

Mouse monoclonal [11G7] antibody to TLR2 (PE).

This antibody recognises the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2. Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Monoclonal

11G7

IgG1

Protein A affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD282 antibody, clone 11G7 recognizes the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (Sandor et al. 2003). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

CD282, TIL4, Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4

This product is for research use only. It is not intended for diagnostic or therapeutic use.