Anti-TLR9 Antibody (A283007)

Anti-TLR9 Antibody

Rabbit polyclonal antibody to TLR9.

This antibody recognises human CD289, otherwise known as toll receptor 9, a member of the evolutionarily conserved toll-like receptor family (TLRs), which play an important role in the recognition of invading microbial pathogens during innate immunity.CD289 is expressed preferentially by the spleen, lymph node, bone marrow and peripheral blood leucocytes and recognises viral DNA and unmethylated CpG sequences in bacterial DNA. Unlike other TLRs, TLR9 is dependant upon the adaptor molecule MyD88 for signaling activation.Rabbit anti Human CD289 antibody has been shown as suitable for use in IHC on human Jurkat cell cytospins @ 2ug/ml.

WB, IHC-Fr

WB: 0.5 - 1 µg/ml

Human, Mouse, Rat

Synthetic peptide corresponding to 15 amino acids near the centre of human CD289.

Rabbit

Polyclonal

IgG

Approximately 95 kDa in human Jurkat cell lysates . (Predicted Mwt. 115-120 kDa).

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human CD289 antibody recognizes human CD289, otherwise known as toll receptor 9, a member of the evolutionarily conserved toll-like receptor family (TLRs), which play an important role in the recognition of invading microbial pathogens during innate immunity.CD289 is expressed preferentially by the spleen, lymph node, bone marrow and peripheral blood leucocytes and recognizes viral DNA and unmethylated CpG sequences in bacterial DNA. Unlike other TLRs, TLR9 is dependant upon the adaptor molecule MyD88 for signaling activation.Rabbit anti Human CD289 antibody has been shown as suitable for use in IHC on human Jurkat cell cytospins @ 2ug/ml.

CD289, Toll-like receptor 9