This antibody recognises tumor necrosis factor receptor type 1-associated DEATH domain protein also known as TRADD. TRADD belongs to the death receptor family of proteins and is an adaptor molecule that interacts with TRANSF1A/TNFR1. TRADD plays a key role in apoptosis and NF-kappaB activation.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:200, WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human TRADD.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 34 kDa and 29 kDa in cell lysates and in tissue under reducing conditions, corresponding to both TRADD isoforms.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti TRADD antibody recognizes tumor necrosis factor receptor type 1-associated DEATH domain protein also known as TRADD. TRADD belongs to the death receptor family of proteins and is an adaptor molecule that interacts with TRANSF1A/TNFR1. TRADD plays a key role in apoptosis and NF-kappaB activation.
Synonyms
TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tumor necrosis factor receptor type 1-associated DEATH domain protein
