This antibody recognises PHD finger protein 20, also known as hepatocellular carcinoma-associated antigen 58 or transcription factor TZP.PHF20 functions as a transcriptional regulator of genes targeted by the MYST family of histone acetyltransferases and is a core component of the male absent on the first (MOF)- non-specific lethal (NSL) lysine acetyltransferase complex. The MOF-NSL complex acetylates histone H4 at lysine 16 and is required for transcriptional regulation and DNA repair.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human, Mouse
Immunogen
A peptide derived from human PHF20.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human PHF20 antibody recognizes PHD finger protein 20, also known as hepatocellular carcinoma-associated antigen 58 or transcription factor TZP.PHF20 functions as a transcriptional regulator of genes targeted by the MYST family of histone acetyltransferases and is a core component of the male absent on the first (MOF)- non-specific lethal (NSL) lysine acetyltransferase complex. The MOF-NSL complex acetylates histone H4 at lysine 16 and is required for transcriptional regulation and DNA repair (Klein et al. 2016).
Western Blot analysis of F9 retinoic acid -treated mouse teratocarcinoma stem cell nuclear extract (20 µg) probed with Anti-TZP Antibody (A320166) at a 1/500 dilution.
Publishing research using Anti-TZP Antibody (A320166)? Please let us know so that we can list the citation on this page.
Proteins predicted to interact with PHF20
Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.