This antibody recognises PHD finger protein 20, also known as hepatocellular carcinoma-associated antigen 58 or transcription factor TZP.PHF20 functions as a transcriptional regulator of genes targeted by the MYST family of histone acetyltransferases and is a core component of the male absent on the first (MOF)- non-specific lethal (NSL) lysine acetyltransferase complex. The MOF-NSL complex acetylates histone H4 at lysine 16 and is required for transcriptional regulation and DNA repair.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human, Mouse
Immunogen
A peptide derived from human PHF20.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human PHF20 antibody recognizes PHD finger protein 20, also known as hepatocellular carcinoma-associated antigen 58 or transcription factor TZP.PHF20 functions as a transcriptional regulator of genes targeted by the MYST family of histone acetyltransferases and is a core component of the male absent on the first (MOF)- non-specific lethal (NSL) lysine acetyltransferase complex. The MOF-NSL complex acetylates histone H4 at lysine 16 and is required for transcriptional regulation and DNA repair (Klein et al. 2016).
Western Blot analysis of F9 retinoic acid -treated mouse teratocarcinoma stem cell nuclear extract (20 µg) probed with Anti-TZP Antibody (A320166) at a 1/500 dilution.
Proteins predicted to interact with PHF20
Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.
