Anti-Vitronectin / S-Protein Antibody [8E6 (1.110)] (A279547)

Anti-Vitronectin / S-Protein Antibody [8E6 (1.110)]

Mouse monoclonal [8E6 (1.110)] antibody to Vitronectin / S-Protein.

This antibody recognises human vitronectin and will react with the native and denatured forms. Mouse anti Human vitronectin antibody, clone 8E6 does not cross react with fibronectin.Vitronectin is an important cell adhesive protein, found in the blood and extracellular matrix. It exists as a mixture of two monomeric glycoproteins that mediate cell adhesion through an interaction between the R-G-D motif, present in the cell binding domains, and several different integrin receptors. Vitronectin is also known as a complement lysis inhibitor and as a scavenger protein for macromolecular products of the complement and homeostasis cascades.

ELISA, IHC-Fr, WB

ELISA: 5 µg/ml - 20 µg/ml, IHC-Fr: 5 µg/ml - 20 µg/ml, WB: 5 µg/ml - 20 µg/ml

Human

Purified vitronectin from human plasma.

Mouse

Monoclonal

8E6 (1.110)

IgG1

Protein G affinity chromatography of ascites.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human vitronectin antibody, clone 8E6 recognizes human vitronectin and will react with the native and denatured forms. Mouse anti Human vitronectin antibody, clone 8E6 does not cross react with fibronectin.Vitronectin is an important cell adhesive protein, found in the blood and extracellular matrix. It exists as a mixture of two monomeric glycoproteins that mediate cell adhesion through an interaction between the R-G-D motif, present in the cell binding domains, and several different integrin receptors. Vitronectin is also known as a complement lysis inhibitor (Milis et al. 1993) and as a scavenger protein for macromolecular products of the complement and homeostasis cascades (Stanley et al. 1986).