ED50: <50 ng/ml, as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B (NFkappaB) in RAW 264.7 cells, corresponding to a specific activity of >2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.
Purity
>98% as determined by RP-HPLC and SDS-PAGE.
Product Form
Lyophilized
Concentration
Reconstitution dependent.
Formulation
Lyophilized from 20 mM Tris HCl Buffer, pH 8, with 150 mM Sodium Chloride.
Storage
Shipped at ambient temperature. Lyophilized: Short term (3 weeks) store at 25°C. Long term store desiccated below -18°C. Reconstituted: Short term (2-7 days) store at 4°C. Long term store below -18°C, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.
Synonyms
CD265, ODFR, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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