Recombinant Rabbit IL-17A Protein (A320548)

Lyophilized

Reconstitution dependent.

Supplied in Phosphate Buffered Saline with 10% Trehalose.

Reconstitute with 20 µl of sterile Phosphate Buffered Saline containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Recombinant Rabbit interleukin-17A is a recombinant protein corresponding to aa 24 - 153 of rabbit interleukin-17A (IL-17A). IL-17A is a disulfide-linked homodimer and member of the IL-17 family, secreted primarily by activated CD4+ T cells, which signal through the IL-17 receptor (IL-17R).IL-17 induces a variety of target cells to secrete inflammatory cytokines, including IL-1ß, IL-6, TNFa, IFN? and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists.

CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL17, IL17A, Interleukin-17A