This antibody recognises rabbit Exodus-2, also widely known as C-C motif chemokine 21 (CCL21), an 111 amino acid CC chemokine which, like CCL19 (small inducible cytokine A19), signals through the CCR7 receptor.Exodus-2 is expressed in the HEV and T cell rich areas of lymph nodes and Peyer’s patches, T cell areas of the spleen and by lymphatic endothelium of many organs; acting as a potent chemoattractant for thymocytes and T lymphocytes. Exodus-2 possesses characteristics of a homing molecule for lymphocytes to secondary lymphoid organs and has been shown to inhibit hematopoiesis.

Applications

WB, ELISA

Dilutions

ELISA: 1 µg/ml - 5 µg/ml, WB: 0.1 µg/ml - 2 µg/ml

Reactivity

Rabbit

Immunogen

Recombinant rabbit CCL21 / Exodus-2.

Host

Chicken

Clonality

Polyclonal

Isotype

IgY

Conjugate

Unconjugated

Concentration

1 mg/ml

Product Form

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Storage

Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

General Notes

Chicken anti Rabbit Exodus-2 antibody recognizes rabbit Exodus-2, also widely known as C-C motif chemokine 21 (CCL21), an 111 amino acid CC chemokine which, like CCL19 (small inducible cytokine A19), signals through the CCR7 receptor.Exodus-2 is expressed in the HEV and T cell rich areas of lymph nodes and Peyer’s patches, T cell areas of the spleen and by lymphatic endothelium of many organs; acting as a potent chemoattractant for thymocytes and T lymphocytes. Exodus-2 possesses characteristics of a homing molecule for lymphocytes to secondary lymphoid organs and has been shown to inhibit hematopoiesis.

Synonyms

6Ckine, Beta-chemokine exodus-2, C C motif chemokine ligand 21, C-C motif chemokine 21, CCL21_HUMAN, Chemokine (C-C motif) ligand 21, Chemokine CC motif ligand 21, CKb9, ECL, Efficient Chemoattractant for Lymphocytes, SCYA21, Secondary lymphoid-tissue chemokine, SLC, Small inducible cytokine A21, Small inducible cytokine subfamily A (Cys-Cys), member 21, Small-inducible cytokine A21, TCA4, UNQ784/PRO1600

Isotype Controls