Anti-CD11c Antibody [BAQ153A] (A279780)

Anti-CD11c Antibody [BAQ153A]

Mouse monoclonal [BAQ153A] antibody to CD11c.

This antibody recognises bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection. Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC and flow cytometry.

Flow Cytometry, ICC

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Bovine, Goat, Sheep, Bison, Water Buffalo

Cells from multiple species.

Mouse

Monoclonal

BAQ153A

IgM

Unconjugated

0.2µM sterile filtered.

Liquid

Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide.

Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Bovine CD11c, clone BAQ153A, recognizes bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection (Sei et al. 2016). Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC (Palmer et al. 2011) and flow cytometry (Sei et al. 2016).

95, 95 alpha chain, CD 11c, CD11 antigen like family member C, CD11 antigen-like family member C, CD11c antigen, Complement component 3 receptor 4 subunit, CR4, Integrin alpha X, Integrin alpha X chain, Integrin alpha-X, Integrin aX, Integrin subunit alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit, ITAX_HUMAN, ITGAX, Leu M5, LEU M5 alpha subunit, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150, Leukocyte adhesion receptor p150 95, Leukocyte surface antigen p150 95 alpha subunit, Leukocyte surface antigen p150 alpha subunit, Myeloid membrane antigen alpha subunit, p150, p150 95 integrin alpha chain, p150/95, SLEB6