Mouse monoclonal [HP-3G10] antibody to CD161 (Alexa Fluor® 488).
Specificity
This antibody recognizes an extracellular epitope of CD161, a type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes, and a subset of T cells as a disulphide-linked homodimer.
Applications
Flow Cytometry, WB
Dilutions
Flow Cytometry: This reagent is designed for analysis of human blood cells using 4µl reagent / 100µl of whole blood or 106 cells in a suspension.
Reactivity
Human, Non-Human Primates
Immunogen
Human NK cells.
Host
Mouse
Clonality
Monoclonal
Clone ID
HP-3G10
Isotype
IgG1
Conjugate
Alexa Fluor® 488
Excitation: 490nm, Emission: 525nm
Purification
This antibody is conjugated with Alexa Fluor® 488 under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage
Store in the dark at 2-8°C. Do not freeze!
Synonyms
C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, KLRB1, Natural killer cell surface protein P1A, NKR-P1A, NKRP1A
Separation of human CD161 positive CD4 negative lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis of human peripheral whole blood stained with Anti-CD161 Antibody [HP-3G10] (Alexa Fluor® 488) (4µl reagent / 100µl of peripheral whole blood).
Proteins predicted to interact with CD161
Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.