Anti-CD200R Antibody [OX-110] (PE) (A281390)

Anti-CD200R Antibody [OX-110] (PE)

Rat monoclonal [OX-110] antibody to CD200R (PE).

This antibody recognises mouse CD200R, a cell surface glycoprotein (also known as OX2R. Mouse CD200R is a 326 amino acid, ~48 kDa single pass type I transmembrane glycoprotein, expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells. CD200-CD200R interaction may be involved in the control of myeloid cellular function. Rat anti Mouse CD200R antibody, clone OX-110 has been used successfully for the immunohistochemical detection of CD200R expressing cells on acetone fixed cryosections of murine synovial tissue.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).

Mouse

Fusion protein mCD200RCD4d3+4.

Rat

Monoclonal

OX-110

IgG2a

Protein G affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Pack Size of 25 Tests: Reconstitute with 0.25 ml of distilled water. Pack Size of 100 Tests: Reconstitute with 1 ml of distilled water

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Rat anti Mouse CD200R antibody, clone OX-110 recognizes mouse CD200R, a cell surface glycoprotein (also known as OX2R. Mouse CD200R is a 326 amino acid, ~48 kDa single pass type I transmembrane glycoprotein, expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (Wright et al.2003). CD200-CD200R interaction may be involved in the control of myeloid cellular function (Minas and Liversidge 2006).Rat anti Mouse CD200R antibody, clone OX-110 has been used successfully for the immunohistochemical detection of CD200R expressing cells on acetone fixed cryosections of murine synovial tissue (Simelyte et al. 2008).

CD 200R, CD200 cell surface glycoprotein receptor, CD200 receptor 1, Cd200r1, Cell surface glycoprotein CD200 receptor 1, Cell surface glycoprotein OX2 receptor, Cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200, CRTR 2, CRTR2, HCRTR2, MO2R1_HUMAN, MOX2 receptor, MOX2R, OX2R

This product is for research use only. It is not intended for diagnostic or therapeutic use.