Anti-CD226 Antibody [DX11] - BSA and Azide free (A280277)

Anti-CD226 Antibody [DX11] - BSA and Azide free

Mouse monoclonal [DX11] antibody to CD226.

This antibody recognises human CD226, a ~65 kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Mouse anti Human CD226 antibody, clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

IP, Flow Cytometry, Functional Assays

Flow Cytometry: 1:25 for 0.1 mg, 1:50 for 0.2 mg - 1:100 for 0.1 mg, 1:200 for 0.2 mg, Use 10µl of the suggested working dilution to label 1 x 10⁶ cells in 100µl

Human

Human cytotoxic T lymphocyte clone.

Mouse

Monoclonal

DX11

IgG1

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD226 antibody, clone DX11 recognizes human CD226, a ~65 kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Mouse anti Human CD226 antibody, clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells (Kojima et al. 2003).

adhesion glycoprotein, CD226 antigen, CD226 molecule, CD226_HUMAN, DNAM 1, DNAM-1, DNAM1, DNAX accessory molecule 1, platelet and T cell activation antigen 1, PTA1, T lineage specific activation antigen 1 antigen, TLiSA1