Mouse monoclonal [UIC2] antibody to CD243 (Alexa Fluor® 647).
Specificity
This antibody recognizes an extracellular epitope on CD243, an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multi-drug resistant cancer cells. This antibody preferentially recognizes CD243 in the process of transporting substrate.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: This reagent is designed for analysis of human blood cells using 4µl reagent / 100µl of whole blood or 106 cells in a suspension.
Reactivity
Human
Cross Reactivity
This antibody does not react with Mouse and Rat.
Immunogen
NIH 3T3 cells transfected with human CD243 cDNA.
Host
Mouse
Clonality
Monoclonal
Clone ID
UIC2
Isotype
IgG2a
Conjugate
Alexa Fluor® 647
Excitation: 650nm, Emission: 665nm
Purification
This antibody is conjugated with Alexa Fluor® 647 under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage
Store in the dark at 2-8°C. Do not freeze!
Synonyms
ABCB1, ATP-binding cassette sub-family B member 1, ATP-dependent translocase ABCB1, EC:7.6.2.2, MDR1, Multidrug resistance protein 1, P-glycoprotein 1, PGY1, Phospholipid transporter ABCB1