Anti-CD32 Antibody [AT130-5R] (A279706)

Anti-CD32 Antibody [AT130-5R]

Rat monoclonal [AT130-5R] antibody to CD32.

This antibody recognises mouse CD32B also known as FcRIIB. CD32B (FcRIIB) is a low affinity receptor for IgG1, IgG2a and IgG2b type antibodies. Unlike other FcRs, the intracellular domain of CD32 contains a inhibitory signaling motif (ITIM) that can antagonize signal transduction mediated through other activatory receptors. FcRIIB is expressed on all myeloid populations and on B-cells.Rat anti Mouse CD32B antibody, clone AT130-5R is a rat IgG2b antibody derived from the parental AT130-5 mouse clone previously described. The binding characteristics of the clone are described in the original publication.

IHC-Fr: 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl

Mouse

Mouse CD32-Rat CD4 fusion protein.

Rat

Monoclonal

AT130-5R

IgG2b

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Supplied in TRIS Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Mouse CD32B antibody, clone AT130-5R recognizes mouse CD32B also known as FcRIIB. CD32B (FcRIIB) is a low affinity receptor for IgG1, IgG2a and IgG2b type antibodies. Unlike other FcRs, the intracellular domain of CD32 contains a inhibitory signaling motif (ITIM) that can antagonize signal transduction mediated through other activatory receptors. FcRIIB is expressed on all myeloid populations and on B-cells.Rat anti Mouse CD32B antibody, clone AT130-5R is a rat IgG2b antibody derived from the parental AT130-5 mouse clone previously described. The binding characteristics of the clone are described in the original publication (Williams et al. 2012).

CD32A, CD32B, CD32C, CDw32, Fc fragment of IgG low affinity IIa receptor, Fc fragment of IgG low affinity IIa receptor for (CD32), Fc fragment of IgG low affinity IIb receptor, Fc fragment of IgG low affinity IIb receptor for (CD32), Fc fragment of IgG low affinity IIc receptor, Fc fragment of IgG low affinity IIc receptor for (CD32), Fc fragment of IgG, low affinity II, receptor for (CD32), Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc gamma receptor IIB, Fc gamma receptor IIC, Fc gamma RII a, Fc gamma RII b, Fc gamma RII c, Fc gamma RIIb, Fc gamma RIIc, Fc receptor, IgG, low affinity IIb, Fc-gamma RII-a, Fc-gamma RII-b, Fc-gamma RII-c, Fc-gamma-RIIa, FC-gamma-RIIB, Fc-GAMMA-RIIC, FCG2, FCG2A_HUMAN, FcGR, FCGR2, FCGR2A, FCGR2A1, FCGR2B, FCGR2C, Fcgr3, Fcgr3a, FcgRII, Fcr-2, Fcr-3, FCRII, FcRII a, FcRII b, FcRII c, FcRII-a, FcRIIC, Fc[g]RII, IGFR2, IgG Fc receptor II a, IgG Fc receptor II b, IgG Fc receptor II beta, IgG Fc receptor II c, IgG Fc receptor II-a, IgG Fc receptor II-b, IgG Fc receptor II-c, Immunoglobulin G Fc receptor II, Immunoglobulin G Fc receptor II c, Low affinity immunoglobulin gamma Fc region receptor II, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c, Ly-17, Ly-m20, LyM-1, Lymphocyte antigen 17