Anti-CD35 Antibody [To5] - BSA and Azide free (A251442)

Mouse monoclonal [To5] antibody to CD35 for Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD35 Antibody [To5] - BSA and Azide free
Description
Mouse monoclonal [To5] antibody to CD35.
Specificity
This antibody recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human CR1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
To5
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
210-220 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD35 Antibody [To5] (A248260).
Synonyms
C3 binding protein, C3b/C4b receptor, C3BR, C4BR, CD 35, CD35 antigen, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3b/4b) receptor 1 including Knops blood group system, Complement component receptor 1, Complement receptor 1, Complement receptor type 1, CR 1, CR1, CR1_HUMAN, KN, Knops blood group antigen
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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