Anti-CD36 Antibody [MF3] (PE) (A281185)

Anti-CD36 Antibody [MF3] (PE)

Rat monoclonal [MF3] antibody to CD36 (PE).

This antibody recognises mouse CD36, also known as platelet glycoprotein 4, glycoprotein IIIb or PAS IV. CD36 is an ~85 kDa multipass transmembrane glycoprotein primarily expressed on platelets, monocytes/macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells.Rat anti Mouse CD36 antibody, clone MF3 has been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrorw derived macrophage fusion.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Mouse

IL-4 treated murine thioglycollate-elicited peritoneal macrophages.

Rat

Monoclonal

MF3

IgG2a

PE

Excitation: 565nm, Emission: 578nm

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Rat anti Mouse CD36 antibody, clone MF3 recognizes mouse CD36, also known as platelet glycoprotein 4, glycoprotein IIIb or PAS IV. CD36 is an ~85 kDa multipass transmembrane glycoprotein primarily expressed on platelets, monocytes/macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells.Rat anti Mouse CD36 antibody, clone MF3 has been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrorw derived macrophage fusion.

Adipocyte membrane protein, BDPLT10, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule, CD36 molecule (thrombospondin receptor), CD36_HUMAN, CHDS7, Cluster determinant 36, Collagen receptor, platelet, FAT, Fatty acid translocase, Fatty acid transport protein, Glycoprotein IIIb, GP IIIb, GP3B, GP4, GPIIIB, GPIV, Leukocyte differentiation antigen CD36, MGC108510, MGC91634, PAS 4 protein, PAS IV, PAS-4, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, scarb3, Scavenger receptor class B member 3, Thrombospondin receptor

This product is for research use only. It is not intended for diagnostic or therapeutic use.