Anti-CD3G Antibody [CD3G/8794] - BSA and Azide free (A316086)

$765

Mouse monoclonal [CD3G/8794] antibody to CD3G for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD3G Antibody [CD3G/8794] - BSA and Azide free
Description
Mouse monoclonal [CD3G/8794] antibody to CD3G.
Specificity
The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of g and e chains (ge), a heterodimer of d and e chains (de) and a homodimer of two z chains (zz) or a heterodimer of z and h chains (zh). The z and h chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The g, e and d chains each contain a single copy of a conserved immunoreceptor tyrosinebased activation motif (ITAM). In contrast, the z chain contains three consecutive copies of the same motif. Phosphorylated ITAMs act as docking sites for protein kinases such as ZAP-70 and Syk and are also capable of regulating their kinase activity. The crystal structure of the ZAP-70 SH2 domains bound to the z chain ITAMs has been solved.
Applications
IHC-P
Positive Control
Human colon, tonsil or spleen.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 1-182) of human CD3G protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
CD3G/8794
Isotype
IgG2c
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
18-28 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CD3 gamma, CD3-GAMMA, CD3g antigen gamma polypeptide, CD3g antigen gamma polypeptide (TiT3 complex), CD3g molecule gamma, CD3g molecule gamma (CD3 TCR complex), CD3G_HUMAN, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T cell antigen receptor complex gamma subunit of T3, T-cell receptor T3 gamma chain, T-cell surface glycoprotein CD3 gamma chain, T3G
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-CD3G Antibody [CD3G/8794] - BSA and Azide free (A316086)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-CD3G Antibody [CD3G/8794] - BSA and Azide free (A316086)

Top