Anti-CD41 Antibody [PM6/248] (FITC) (A281572)

$420

Mouse monoclonal [PM6/248] antibody to CD41 (FITC) for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD41 Antibody [PM6/248] (FITC)
Description
Mouse monoclonal [PM6/248] antibody to CD41 (FITC).
Specificity
This antibody recognises the human CD41 cell surface antigen, a ~140 kDa glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.It has not been established if clone PM6/248 recognises free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 100µl whole blood.
Reactivity
Human, Baboon
Immunogen
Human platelet plasma membranes.
Host
Mouse
Clonality
Monoclonal
Clone ID
PM6/248
Isotype
IgG1
Conjugate

FITC

Excitation: 490nm, Emission: 525nm

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
General Notes
Mouse anti Human CD41 antibody, clone PM6/248 recognizes the human CD41 cell surface antigen, a ~140 kDa glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
Synonyms
antigen CD41, BDPLT16, BDPLT2, CD41B, form 2, GP2B, GPalpha IIb, GPIIb, GT, GTA, HPA3, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-IIb light chain, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), ITA2B_HUMAN, Itga2b, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex, Platelet membrane glycoprotein IIb, platelet specific antigen BAK, PPP1R93
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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