Anti-CD46 Antibody [6D8/8] (A279485)

Anti-CD46 Antibody [6D8/8]

Mouse monoclonal [6D8/8] antibody to CD46.

This antibody recognises the porcine CD46 cell surface antigen, a ~50-60 kDa glycoprotein also known as membrane cofactor protein (MCP).Porcine CD46 is expressed on a wide range of cells including leucocytes, platelets and erythrocytes. CD46 serves as an inhibitor of complement activation on host cells. Mouse anti Pig CD46, clone 6D8/8 induces homotypic cell aggregation,. . Mouse anti pig CD46, clone 6D8/8 detects a series of closely apposed bands of approximately 50-60 kDa in pig erythrocyte lysates.

WB, IP, Flow Cytometry

Flow Cytometry: 1:25 - 1:50, Use 10µl of the suggested working dilution to 1x10⁶ cells in 100µl

Porcine

Porcine Peripheral Blood Mononuclear cells.

Mouse

Monoclonal

6D8/8

IgG1

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Pig CD46, clone 6D8/8 recognizes the porcine CD46 cell surface antigen, a ~50-60 kDa glycoprotein also known as membrane cofactor protein (MCP).Porcine CD46 is expressed on a wide range of cells including leucocytes, platelets and erythrocytes. CD46 serves as an inhibitor of complement activation on host cells.Mouse anti Pig CD46, clone 6D8/8 induces homotypic cell aggregation, (Bullido et al. 2000). .Mouse anti pig CD46, clone 6D8/8 detects a series of closely apposed bands of approximately 50-60 kDa in pig erythrocyte lysates (Perez De La Lastra et al. 1999).

AHUS2, Antigen defined by monoclonal, Antigen identified by monoclonal, CD46 antigen, CD46 antigen complement regulatory protein, CD46 molecule, CD46 molecule complement regulatory protein, Complement membrane cofactor protein, MCP, MCP_HUMAN, Measles virus receptor, Membrane cofactor protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MGC26544, MIC10, TLX, TRA2.10, Trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, Trophoblast lymphocyte cross reactive antigen