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Anti-Transferrin Receptor Antibody [YTA74.4] (PE) (A282068)

This product is discontinued

Anti-Transferrin Receptor Antibody [YTA74.4] (PE) (A282068) has been discontinued and is no longer available.

View all Transferrin Receptor Antibodies.

Name
Anti-Transferrin Receptor Antibody [YTA74.4] (PE)
Description
Rat monoclonal [YTA74.4] antibody to Transferrin Receptor (PE).
Specificity
This antibody recognises the mouse Transferrin receptor protein 1 also known as CD71 or TfR1. CD71 is a 763 amino acid glycoprotein homodimer of ~95 kDa subunits. CD71 is expressed by dividing cells, and functions as a transferrin receptor mediating uptake of iron.Rat anti Mouse CD71 antibody, clone YTA74.4 blocks the binding of R17 217.1.3. and R17 208.2 anti-TFR monoclonal antibodies.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/B).
Reactivity
Mouse
Immunogen
Concanavilin A activated mouse spleen cells.
Host
Rat
Clonality
Monoclonal
Clone ID
YTA74.4
Isotype
IgG2a
Conjugate

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
Reconstitution dependent.
Product Form
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Storage
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rat anti Mouse CD71 antibody, clone YTA74.4 recognizes the mouse Transferrin receptor protein 1 also known as CD71 or TfR1. CD71 is a 763 amino acid glycoprotein homodimer of ~95 kDa subunits. CD71 is expressed by dividing cells, and functions as a transferrin receptor mediating uptake of iron.Rat anti Mouse CD71 antibody, clone YTA74.4 blocks the binding of R17 217.1.3. and R17 208.2 anti-TFR monoclonal antibodies (Trowbridge et al. 1982).
Synonyms
CD71, p90, T9, TfR, TfR1, TFRC, TR, Transferrin receptor protein 1, Trfr
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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99.5% Relevancy Score
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