Anti-CD83 Antibody [3D11] (A279293)

Anti-CD83 Antibody [3D11]

Rat monoclonal [3D11] antibody to CD83.

This antibody recognises mouse CD83, a 45 kDa type 1 glyoprotein belonging to the immunoglobulin superfamily. Originally described as a maturation marker for dendritic cells, CD83 plays a role in the regulation of antigen presentation, thymic T-cell maturation, B-cell function and peripheral T-cell activation. Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, suggesting a therapeutic role for sCD83 in the regulation of immune disorders.

Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Mouse

Rat

Monoclonal

3D11

IgG2a

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Mouse CD83 antibody, clone 3D11 recognizes murine CD83, a 45 kDa type 1 glyoprotein belonging to the immunoglobulin superfamily. Originally described as a maturation marker for dendritic cells, CD83 plays a role in the regulation of antigen presentation, thymic T-cell maturation, B-cell function and peripheral T-cell activation. Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, suggesting a therapeutic role for sCD83 in the regulation of immune disorders.

B cell activation 45kDa cell surface glycoprotein Ig superfamily, B cell activation protein, B-cell activation protein, BL11, BL11 PEN, CD83 antigen, CD83 antigen (activated B lymphocytes, immunoglobulin superfamily), CD83 molecule, CD83_HUMAN, Cell surface glycoprotein, Cell surface protein HB15, HB15, hCD83