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Anti-CD89 Antibody

 
Mouse monoclonal (MIP7c) antibody to CD89 from Absea Biotechnology (010007C01).
Overview
Name: Anti-CD89 Antibody
Description: Mouse monoclonal (MIP7c) antibody to CD89.
Applications: FACS
Reactivity: Human
Immunogen: Soluble CD89.
Host: Mouse
Clonality: Monoclonal
Clone: MIP7c
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Tissue Specificity: Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
Cellular Location: Cell membrane.
UniProt: P24071
Gene ID: 2204
Synonyms: Fc alpha receptor Antibody
Fc fragment of IgA, receptor for Antibody
FCAR Antibody
FCAR_HUMAN Antibody
IgA Fc receptor Antibody
Immunoglobulin alpha Fc receptor Antibody
Information: Target information shown above is from the UniProt Consortium.

Images
Validation Data - Anti-CD89 Antibody from Absea Biotechnology (010007C01) - Antibodies.com
Neutrophil phagocytosis of IgA immune complexes in presence or absence (control) of MIP7c.

Product Citations

Zhang W et al. Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a. Clin. Exp. Immunol. 121(1): 106-111 (2000)


Research Areas

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Please Note: Anti-CD89 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 010007C01
Size Price Quantity
100µg £178
200µg £259
1mg £682

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