Rabbit polyclonal antibody to ATR (Phospho-Ser428)
Specificity
The antibody detects endogenous levels of ATR only when phosphorylated at serine 428.
Applications
IHC, ICC/IF
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of serine 428 (G-I-S(p)-P-K) derived from Human ATR.
Host
Rabbit
Clonality
Polyclonal
Conjugate
Unconjugated
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1.0 mg/mL
Formulation
Supplied in phosphate-buffered saline (without Mg²? and Ca²?), pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Synonyms
Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, FRP1, Serine/threonine-protein kinase ATR
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ATR (Phospho-Ser428) antibody #12129. The picture on the right is treated with the synthesized peptide.
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