Anti-CD3 epsilon Antibody [PC3/188A] (A250493)

Mouse monoclonal [PC3/188A] antibody to CD3 epsilon for Flow Cytometry, IF and WB.

Alternative Formats and ConjugatesAlternative Formats

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Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
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Highlighted products for Anti-CD3 epsilon Antibody

Name
Anti-CD3 epsilon Antibody [PC3/188A]
Description
Mouse monoclonal [PC3/188A] antibody to CD3 epsilon.
Specificity
This antibody recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Applications
Flow Cytometry, IF, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivity
Human, Rat, Guinea Pig, Rabbit, Porcine, Horse, Bovine, Chicken
Immunogen
Synthetic peptide corresponding to amino acids 156-168 of the cytoplasmic domain of human CD3 epsilon chain.
Host
Mouse
Clonality
Monoclonal
Clone ID
PC3/188A
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
20 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD3 epsilon Antibody [PC3/188A] - BSA and Azide free (A253673).
Synonyms
CD3e, CD3E antigen epsilon polypeptide, CD3e antigen epsilon polypeptide (TiT3 complex), CD3E antigen, epsilon subunit, CD3e molecule epsilon, CD3e molecule, epsilon (CD3 TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3E_HUMAN, IMD18, T cell antigen receptor complex epsilon subunit of T3, T cell surface antigen T3/Leu 4 epsilon chain, T cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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