Phosphate CPG is a solid support for the synthesis of 3'-phosphorylated oligonucleotides. The phosphate group can be used as a blocking functionality to prevent 3'-5' exonuclease activity of some polymerases. Upon cleavage from the support, a phosphate group remains at the 3' end of the oligonucleotide. It does not require any changes in oligo synthesis and deprotection protocols.
Purity
95% (by 1H NMR, HPLC-MS, and functional testing in oligo synthesis).
Product Form
Off-white beads.
Storage
Shipped at room temperature. Upon delivery, store in the dark at -20°C. Avoid prolonged exposure to light. Desiccate.
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
