Recombinant Anti-Collagen II Antibody [COL2A1/8882R] (A314806)

$765

Recombinant rabbit monoclonal [COL2A1/8882R] antibody to Collagen II for ELISA and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Collagen II Antibody [COL2A1/8882R]
Description
Recombinant rabbit monoclonal [COL2A1/8882R] antibody to Collagen II.
Specificity
The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.
Applications
ELISA, IHC-P
Positive Control
Human cartilage, lung or eye.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human COL2A1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
COL2A1/8882R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
190 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Alpha 1 type II collagen, Alpha-1 type II collagen, AOM, Cartilage collagen, Chondrocalcin, CO2A1_HUMAN, COL11A3, Col2a1, Collagen II alpha 1 polypeptide, SEDC
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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