Anti-CREB5 Antibody [PCRP-CREB5-1G8] (A250809)

Mouse monoclonal [PCRP-CREB5-1G8] antibody to CREB5 for Flow Cytometry, IF and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CREB5 Antibody [PCRP-CREB5-1G8]
Description
Mouse monoclonal [PCRP-CREB5-1G8] antibody to CREB5.
Specificity
The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
Applications
Flow Cytometry, IF, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human CREB5 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-CREB5-1G8
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
57 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CREB5 Antibody [PCRP-CREB5-1G8] - BSA and Azide free (A253989).
Synonyms
cAMP response element binding protein 5, cAMP response element binding protein CRE Bpa, cAMP response element-binding protein CREBPa, cAMP responsive element binding protein 5, cAMP responsive element binding protein 5 isoform alpha, cAMP-responsive element-binding protein 5, CRE BPA, CRE-BPa, CREB 5, CREB-5, CREB5_HUMAN, CREBPA, cyclic AMP responsive element binding protein 5, Cyclic AMP-responsive element-binding protein 5
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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