Anti-CXCL2 Antibody - BSA and Azide free (A283920)

$645

Rabbit polyclonal antibody to CXCL2 for WB, ELISA, IHC-P and Functional Assays.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CXCL2 Antibody - BSA and Azide free
Description
Rabbit polyclonal antibody to CXCL2.
Specificity
This antibody recognises human GRO-beta, also known as Growth-regulated protein beta, C-X-C motif chemokine 2, Macrophage inflammatory protein 2-alpha, MIP-2a or CXCL2. GRO beta is a ~7.9 kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, GRO-beta has a lower potency and receptor binding affinity.
Applications
WB, ELISA, IHC-P, Functional Assays
Dilutions
ELISA: 0.5 µg/ml, Functional Assays: 0.5 - 1 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant human GRO-beta.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human GRO beta antibody recognizes human GRO-beta, also known as Growth-regulated protein beta, C-X-C motif chemokine 2, Macrophage inflammatory protein 2-alpha, MIP-2a or CXCL2. GRO beta is a ~7.9 kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, GRO-beta has a lower potency and receptor binding affinity (Geiser et al. 1993).
Synonyms
C-X-C motif chemokine 2, Chemokine (C X C motif) ligand 2, Chemokine (C-X-C motif) ligand 2, Chemokine, CXC motif, ligand 2, CINC 2a, CINC-2a, CINC2a, CINC3, CXC chemokine, CXCL 2, CXCL2_HUMAN, Cytokine-induced neutrophil chemoattractant 3, GRO 2, GRO b, Gro beta, GRO protein, beta, Gro-beta, GRO-beta(5-73), GRO-beta-T, GRO2, GRO2 oncogene, GROb, GRObeta, Growth regulated protein beta, Growth-regulated protein beta, GROX, Hematopoietic synergistic factor, HSF, Macrophage inflammatory protein 2, Macrophage inflammatory protein 2 alpha, Macrophage inflammatory protein 2-alpha, Melanoma growth stimulatory activity beta, MGSA b, MGSA beta, MGSA-b, MIP 2, MIP 2a, MIP2, MIP2 alpha, MIP2-alpha, MIP2A, MIP2alpha, SB-251353, Scyb, SCYB 2, SCYB2, Small inducible cytokine subfamily B, member 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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