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Anti-CYP17A1 Antibody

Rabbit polyclonal antibody to CYP17A1 from ABclonal (A1373).
Name: Anti-CYP17A1 Antibody
Description: Rabbit polyclonal antibody to CYP17A1.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human CYP17A1.
Protein Length: 508
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Involvement in Disease: Adrenal hyperplasia 5: A form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by androgen excess leading to ambiguous genitalia in affected females, rapid somatic growth during childhood in both sexes with premature closure of the epiphyses and short adult stature. Four clinical types: 'salt wasting' (SW, the most severe type), 'simple virilizing' (SV, less severely affected patients), with normal aldosterone biosynthesis, 'non-classic form' or late-onset (NC or LOAH) and 'cryptic' (asymptomatic).
Sequence Similarities: Belongs to the cytochrome P450 family.
Post-Translational Modification: Phosphorylation is necessary for 17,20-lyase, but not for 17-alpha-hydroxylase activity.
Cellular Location: Membrane.
UniProt: P05093
Gene ID: 1586
Synonyms: 20 lyase Antibody
CP17A_HUMAN Antibody
CPT7 Antibody
CYP17 Antibody
CYPXVII Antibody
Cytochrome P450 17A1 Antibody
Cytochrome P450 family 17 Antibody
Cytochrome P450 family 17 subfamily A polypeptide 1 Antibody
Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia Antibody
Cytochrome p450 XVIIA1 Antibody
Cytochrome P450-C17 Antibody
Cytochrome P450c17 Antibody
OTTHUMP00000020382 Antibody
P450 C17 Antibody
P450c17 Antibody
S17AH Antibody
Steroid 17 alpha hydroxylase/17,20 lyase Antibody
Steroid 17 alpha monooxygenase Antibody
Steroid 17-alpha-hydroxylase/17 Antibody
Steroid 17-alpha-monooxygenase Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of various cells, using CYP17A1 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (3)
Description: Goat polyclonal antibody to CYP17A1.
Application: ELISA, WB, IHC
Host: Goat
Isotype: IgG
Reactivity: Human

£205

Description: Rabbit polyclonal antibody to CYP17A1 (N249)
Application: WB, IHC, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 211-260 of Human CYP17A1.

£165 – £283

Description: Rabbit polyclonal antibody to CYP17A1
Application: IHC
Host: Rabbit
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human cytochrome P450, family 17, subfamily A, polypeptide 1

£234

Description: Mouse monoclonal antibody to CYP17A1
Application: WB
Host: Mouse
Reactivity: Human
Immunogen: Recombinant full length Human CYP17A1.

£220 – £366

Please Note: Anti-CYP17A1 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A1373
Size Price Quantity
50µl £148
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe