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Anti-CYP4F2 Antibody

Rabbit polyclonal antibody to CYP4F2 from ABclonal (A10128).
Name: Anti-CYP4F2 Antibody
Description: Rabbit polyclonal antibody to CYP4F2.
Applications: WB
Dilutions: WB: 1:500 - 1:2000.
Reactivity: Human
Immunogen: Recombinant protein of human CYP4F2.
Protein Length: 520
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
Tissue Specificity: Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).
Involvement in Disease: Coumarin resistance: A condition characterized by partial or complete resistance to warfarin or other 4-hydroxycoumarin derivatives. These drugs are used as anti-coagulants for the prevention of thromboembolic diseases in subjects with deep vein thrombosis, atrial fibrillation, or mechanical heart valve replacement.
Sequence Similarities: Belongs to the cytochrome P450 family.
Cellular Location: Microsome membrane. Endoplasmic reticulum membrane.
UniProt: P78329
Gene ID: 8529
Synonyms: Cyp4f14 Antibody
CYPIVF1 Antibody
Cytochrome P450 LTB omega Antibody
Cytochrome P450, family 4, subfamily F, polypeptide 2 Antibody
EC Antibody
Leukotriene B(4) 20 monooxygenase Antibody
Leukotriene B(4) omega hydroxylase Antibody
MGC126966 Antibody
MGC93476 Antibody
P450 A3 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of various cells, using CYP4F2 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Rabbit polyclonal antibody to CYP4F2 (M66)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 36-90 of Human CYP4F2.

£165 – £283

Description: Rabbit polyclonal antibody to CYP4F2
Application: WB, IHC, ICC, IP
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 76-121 of Human CYP4F2.

£165 – £283

Please Note: Anti-CYP4F2 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A10128
Size Price Quantity
50µl £148
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
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