Recombinant Anti-Cytokeratin 7 Antibody [KRT7/8121R] (A314873)

Anti-Cytokeratin 7 Antibody [KRT7/8121R]

Recombinant rabbit monoclonal [KRT7/8121R] antibody to Cytokeratin 7.

Cytokeratin 7 in humans is a protein encoded by the KRT7 gene. It is always as a keratin pair with Cytokeratin 19. Cytokeratin 7 is expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. In tumor tissues, its expression is absent in colon cancer, prostate cancer and squamous carcinomas. Cytokeratin 7 is often used in concert with Cytokeratin 20 and CDX-2 to aid in distinguishing ovarian, pulmonary and breast carcinomas (CK7+) from colon carcinomas (CK7-).

Carcinoma of ovary, lung, cervix, or breast.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human KRT7 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

KRT7/8121R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CK 7, CK-7, CK7, Cytokeratin-7, D15Wsu77e, K2C7, K2C7_HUMAN, K7, Keratin 7, Keratin 7, type II, Keratin type II cytoskeletal 7, Keratin, 55K type II cytoskeletal, Keratin, simple epithelial, Keratin, simple epithelial type I, K7, Keratin, type II cytoskeletal 7, Keratin-7, Krt2-7, KRT7, MGC11625, MGC129731, MGC3625, Sarcolectin, SCL, Type II mesothelial keratin K7, Type-II keratin Kb7