Anti-Daxx Antibody [DAXX-01] (A280226)

$340

Mouse monoclonal [DAXX-01] antibody to Daxx for IHC-Fr, WB and IF.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Daxx Antibody [DAXX-01]
Description
Mouse monoclonal [DAXX-01] antibody to Daxx.
Specificity
This antibody recognises human Death domain-associated protein 6, also known as DAXX, ETS1-associated protein 1, EAP1 or Fas death domain-associated protein. DAXX is a 740 amino acid ~81 kDa nucleoplasmic protein.DAXX is a regulator of apoptosis implicated in Fas and TGF beta induced apoptosis. DAXX is predominantly a nuclear protein, where it as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm.
Applications
IHC-Fr, WB, IF
Reactivity
Human
Immunogen
Recombinant C-terminus DAXX protein, amino acids 558-740.
Sequence
EEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD
Host
Mouse
Clonality
Monoclonal
Clone ID
DAXX-01
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human DAXX antibody, clone DAXX-01 recognizes human Death domain-associated protein 6, also known as DAXX, ETS1-associated protein 1, EAP1 or Fas death domain-associated protein. DAXX is a 740 amino acid ~81 kDa nucleoplasmic protein.DAXX is a regulator of apoptosis implicated in Fas and TGF beta induced apoptosis. DAXX is predominantly a nuclear protein, where it as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm.
Synonyms
, BING 2, BING2, CENP-C binding protein, DAP 6, DAP6, DAXX_HUMAN, Death associated protein 6, Death domain associated protein, Death domain associated protein 6, Death domain-associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, ETS1-associated protein 1, Fas binding protein, Fas death domain associated protein, Fas death domain-associated protein, hDaxx, MGC126245, MGC126246
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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