Anti-DAXX Antibody [PCRP-DAXX-5G11] (A277571)

Mouse monoclonal [PCRP-DAXX-5G11] antibody to DAXX for Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-DAXX Antibody [PCRP-DAXX-5G11]
Description
Mouse monoclonal [PCRP-DAXX-5G11] antibody to DAXX.
Specificity
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human DAXX protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-DAXX-5G11
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
81.37 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-DAXX Antibody [PCRP-DAXX-5G11] - BSA and Azide free (A278159).
Synonyms
, BING 2, BING2, CENP-C binding protein, DAP 6, DAP6, DAXX_HUMAN, Death associated protein 6, Death domain associated protein, Death domain associated protein 6, Death domain-associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, ETS1-associated protein 1, Fas binding protein, Fas death domain associated protein, Fas death domain-associated protein, hDaxx, MGC126245, MGC126246
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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