Anti-DMRT2 Antibody [PCRP-DMRT2-1B11] (A277532)

Mouse monoclonal [PCRP-DMRT2-1B11] antibody to DMRT2 for Flow Cytometry and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-DMRT2 Antibody [PCRP-DMRT2-1B11]
Description
Mouse monoclonal [PCRP-DMRT2-1B11] antibody to DMRT2.
Specificity
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
Applications
Flow Cytometry, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human DMRT2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-DMRT2-1B11
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
62 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-DMRT2 Antibody [PCRP-DMRT2-1B11] - BSA and Azide free (A278120).
Synonyms
DMRT2_HUMAN, Doublesex and mab 3 related transcription factor 2, Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL 2, DSXL-2, DSXL2, terra like protein
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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