Specificity
Rabbit anti EIF4E (pSer209) antibody recognizes the eukaryotic translation initiation factor 4E (EIF4E), also known as eIF-4F 25 kDa subunit or mRNA cap-binding protein, when phosphorylated at serine 209. EIF4E is a member of the eukaryotic initiation factor 4E protein family and is the least abundant component of the eukaryotic translation initiation factor 4F complex (eIF-4F). EIF4E binds to the 5′-cap structure on eukaryotic mRNAs and is phosphorylated at serine 209 by (MAPK) signal-integrating kinase 1 (Mnk1) and (MAPK) signal-integrating kinase 2 (Mnk2) (Scheper et al. 2001).