Anti-Endothelin Antibody [3G10] (A279306)

Anti-Endothelin Antibody [3G10]

Rat monoclonal [3G10] antibody to Endothelin.

This antibody recognises the C terminal of endothelins 1, 2 and 3. Rat anti Human endothelin antibody, clone 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.

IHC-Fr, IRMA

Frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.

Human

Synthetic peptide sequence CHLDIIW corresponding to the C-terminus of human endothelin conjugated to Bovine Serum Albumin.

CHLDIIW

Rat

Monoclonal

3G10

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Human endothelin antibody, clone 3G10 reacts with the C terminal of endothelins 1, 2 and 3. Rat anti Human endothelin antibody, clone 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.