Recombinant Anti-Estrogen Receptor alpha Antibody [ESR1/4039R] - BSA and Azide free (A278564)

Recombinant rabbit monoclonal [ESR1/4039R] antibody to Estrogen Receptor alpha for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Estrogen Receptor alpha Antibody [ESR1/4039R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [ESR1/4039R] antibody to Estrogen Receptor alpha.
Specificity
This antibody recognizes a protein of 67kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to antiestrogen (e.g. tamoxifen) therapy.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment corresponding to the C terminus of human Estrogen Receptor alpha.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ESR1/4039R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
~67 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Estrogen Receptor alpha Antibody [ESR1/4039R] (A277976).
Synonyms
DKFZp686N23123, ER, ER alpha, ER-alpha, Era, ESR, ESR1, ESR1_HUMAN, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor, Estrogen receptor 1, Estrogen receptor alpha 3*,4,5,6,7*/822 isoform, Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform, Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform, Estrogen receptor alpha delta 4 +49 isoform, Estrogen receptor alpha delta 4*,5,6,7*/654 isoform, Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform, Estrogen receptor alpha E1 E2 1 2, Estrogen receptor alpha E1 N2 E2 1 2, ESTRR, NR3A1, Nuclear receptor subfamily 3 group A member 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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