Anti-Estrogen Sulfotransferase Antibody [SULT1E1/7124] (A314938)

Anti-Estrogen Sulfotransferase Antibody [SULT1E1/7124]

Mouse monoclonal [SULT1E1/7124] antibody to Estrogen Sulfotransferase.

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

WB, IHC-P

HEPG2 cells. Human liver, intestine or kidney.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 100-294) of human SULT1E1 protein. The exact sequence is proprietary.

Mouse

Monoclonal

SULT1E1/7124

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

35 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

EST, EST-1, EST1, estrogen-preferring, estrone sulfotransferase, ST1E1, ST1E1_HUMAN, STE, Sulfotransferase, Sulfotransferase 1E1, Sulfotransferase estrogen preferring, Sulfotransferase family 1E member 1, SULT1E1