Anti-Factor B Antibody (HRP)
Mouse monoclonal (KT24) antibody to Factor B (HRP) from Absea Biotechnology (010105E10H).
|Name:||Anti-Factor B Antibody (HRP)|
|Description:||Mouse monoclonal (KT24) antibody to Factor B (HRP).|
|Immunogen:||Purified Factor B from human blood.|
|Purification:||IgG is purified through a Protein A column and then labelled with peroxidase.|
|Concentration:||1 mg/ml in PBS containing 0.01% thimerosal as a preservative.|
|Storage:||4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.|
|Function:||Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.|
|Involvement in Disease:||Hemolytic uremic syndrome atypical 4: An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
Complement factor B deficiency: An immunologic disorder characterized by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway.
|Sequence Similarities:||Belongs to the peptidase S1 family.|
B factor properdin Antibody
C3 proaccelerator Antibody
C3 proactivator Antibody
C3/C5 convertase Antibody
Complement Factor B Antibody
Complement factor B Bb fragment Antibody
Glycine rich beta glycoprotein Antibody
Glycine-rich beta glycoprotein Antibody
H2 Bf Antibody
Properdin factor B Antibody
|Information:||Target information shown above is from the UniProt Consortium.|
Sandwich ELISA usingKT21 coated plate and HRP conjugated KT24.
Please Note: Anti-Factor B Antibody (HRP) is for research use only. It is not intended for diagnostic of therapeutic use.