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Anti-Factor B Antibody (HRP)

 
Mouse monoclonal (KT24) antibody to Factor B (HRP) from Absea Biotechnology (010105E10H).
Overview
Name: Anti-Factor B Antibody (HRP)
Description: Mouse monoclonal (KT24) antibody to Factor B (HRP).
Applications: sELISA 
Reactivity: Human
Immunogen: Purified Factor B from human blood.
Host: Mouse
Clonality: Monoclonal
Clone: KT24
Isotype: IgG1
Conjugate: HRP
Purification: IgG is purified through a Protein A column and then labelled with peroxidase.
Concentration: 1 mg/ml in PBS containing 0.01% thimerosal as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Involvement in Disease: Hemolytic uremic syndrome atypical 4: An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

Complement factor B deficiency: An immunologic disorder characterized by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway.
Sequence Similarities: Belongs to the peptidase S1 family.
Cellular Location: Secreted.
UniProt: P00751
Gene ID: 629
Synonyms: AHUS4 Antibody
B factor properdin Antibody
BF Antibody
BFD Antibody
C3 proaccelerator Antibody
C3 proactivator Antibody
C3/C5 convertase Antibody
CFAB Antibody
CFAB_HUMAN Antibody
CFB Antibody
Complement Factor B Antibody
Complement factor B Bb fragment Antibody
FB Antibody
FBI12 Antibody
GBG Antibody
Glycine rich beta glycoprotein Antibody
Glycine-rich beta glycoprotein Antibody
H2 Bf Antibody
H2BF Antibody
PBF2 Antibody
Properdin factor B Antibody
Information: Target information shown above is from the UniProt Consortium.

Images
Sandwich ELISA - Anti-Factor B Antibody (HRP) from Absea Biotechnology (010105E10H) - Antibodies.com
Sandwich ELISA usingKT21 coated plate and HRP conjugated KT24.


Please Note: Anti-Factor B Antibody (HRP) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 010105E10H
Size Price Quantity
100µg £186
200µg £273
1mg £730

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe