Anti-FK-506 Antibody [FK1] (A280472)

Anti-FK-506 Antibody [FK1]

Mouse monoclonal [FK1] antibody to FK-506.

This antibody recognises FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis.FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.

Species Independent

FK-506-BSA conjugate.

Mouse

Monoclonal

FK1

IgM

1 mg/ml

Liquid

Supplied in TRIS Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at 4°C.

Mouse anti FK-506 antibody, clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis.FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.