Recombinant Anti-FOXL2 Antibody [FOXL2/8362R] (A314975)

Anti-FOXL2 Antibody [FOXL2/8362R]

Recombinant rabbit monoclonal [FOXL2/8362R] antibody to FOXL2.

FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.

Nuclear expression in ovarian follicular and stromal cells. Granulosa cell tumor.

IHC: 1-2 µg/ml

Human

Recombinant full-length human FOXL2 protein.

Rabbit

Monoclonal

FOXL2/8362R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

38 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Blepharophimosis, Blepharophimosis epicanthus inversus and ptosis, Blepharophimosis epicanthus inversus and ptosis 1, BPES, BPES 1, BPES1, Epicanthus inversus and ptosis 1, Forkhead box L2, Forkhead box protein L2, Forkhead transcription factor FOXL2, FOX L2, FOXL 2, FOXL2_HUMAN, PFRK, PINTO, PITUITARY FORKHEAD FACTOR, POF 3, POF3