Anti-G-CSF Antibody [CSF3/4599] (A315008)

$765

Mouse monoclonal [CSF3/4599] antibody to G-CSF for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-G-CSF Antibody [CSF3/4599]
Description
Mouse monoclonal [CSF3/4599] antibody to G-CSF.
Specificity
This MAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF s, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF s share 73% sequence identity at the amino acid level.
Applications
IHC-P
Positive Control
Human tonsil or lymph node.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 1-200) of human CSF3 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
CSF3/4599
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
19 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
C17orf33, Colony stimulating factor 3, Colony stimulating factor 3 (granulocyte), CSF 3, CSF beta , CSF3, CSF3OS, CSF3_HUMAN, Csfg, Filgrastim, GCSA, GCSF, Granulocyte colony stimulating fact, Granulocyte colony stimulating factor, Granulocyte colony-stimulating factor, Lenograstim , Macrophage granulocyte inducer 2, MGC45931, MGI 2, MGI IG, OTTMUSP00000006785, Pluripoietin, RP23-395E10.4
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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