Anti-GAD65 Antibody [GAD2/2362] (A248677)

Mouse monoclonal [GAD2/2362] antibody to GAD65 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com

Highlighted products for Anti-GAD65 Antibody

Name
Anti-GAD65 Antibody [GAD2/2362]
Description
Mouse monoclonal [GAD2/2362] antibody to GAD65.
Specificity
This antibody recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GADs are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 6-99, of human GAD2 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
GAD2/2362
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
65 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-GAD65 Antibody [GAD2/2362] - BSA and Azide free (A251859).
Synonyms
65 kDa glutamic acid decarboxylase, DCE 2, DCE2, DCE2_HUMAN, GAD 2, GAD 65, GAD-2, GAD-65, Gad2, Glutamate decarboxylase 2, Glutamate decarboxylase 2 (pancreas), Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa), Glutamate Decarboxylase 65, Glutamate decarboxylase 65 kDa isoform, Glutamic Acid Decarboxylase 2, Glutamic Acid Decarboxylase 65, MGC161605, MGC161607
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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