Anti-GTF2IRD2 Antibody [PCRP-GTF2IRD2-1B4] (A250415)

Mouse monoclonal [PCRP-GTF2IRD2-1B4] antibody to GTF2IRD2 for Flow Cytometry and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-GTF2IRD2 Antibody [PCRP-GTF2IRD2-1B4]
Description
Mouse monoclonal [PCRP-GTF2IRD2-1B4] antibody to GTF2IRD2.
Specificity
The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
Applications
Flow Cytometry, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human GTF2IRD2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-GTF2IRD2-1B4
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
107 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-GTF2IRD2 Antibody [PCRP-GTF2IRD2-1B4] - BSA and Azide free (A253595).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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