Specificity
This antibody recognises Herpes Simplex virus 1 and 2, recognizing infected cell proteins (ICPs) and late structural (virion) antigens. recognises HEp-2 cells.Herpes Simplex virus (HSV) is a double stranded DNA virus of which there are 2 types, HSV1 and HSV2. HSV1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From the trigeminal ganglion, it tends to recur on the lower lip or face causing cold sores. HSV2 usually resides in the sacral ganglion at the base of the spine. From there, it recurs in the genital area.