Anti-HOXB2 Antibody [PCRP-HOXB2-1F2] (A277644)

Mouse monoclonal [PCRP-HOXB2-1F2] antibody to HOXB2 for ELISA, IP, Flow Cytometry, IF, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-HOXB2 Antibody [PCRP-HOXB2-1F2]
Description
Mouse monoclonal [PCRP-HOXB2-1F2] antibody to HOXB2.
Specificity
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.
Applications
ELISA, IP, Flow Cytometry, IF, WB, IHC-P
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 114-220, of human HOXB2 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-HOXB2-1F2
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
37.9 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HOXB2 Antibody [PCRP-HOXB2-1F2] - BSA and Azide free (A278232).
Synonyms
homeo box 2H, homeo box B2, homeobox B2, Homeobox protein Hox-2.8, Homeobox protein Hox-2H, Homeobox protein Hox-B2, Hox 2 8, Hox 2H, HOX2, HOX2H, HXB2_HUMAN, K8, K8 home protein
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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