Recombinant Anti-HSP60 Antibody [HSPD1/8398R] - BSA and Azide free (A316486)

$765

Recombinant rabbit monoclonal [HSPD1/8398R] antibody to HSP60 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-HSP60 Antibody [HSPD1/8398R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [HSPD1/8398R] antibody to HSP60.
Specificity
Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone HSPD1/8398R, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.
Applications
IHC-P
Positive Control
HeLa or Hep2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human full-length HSP60 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
HSPD1/8398R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
60 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
60 kDa chaperonin, 60 kDa heat shock protein, mitochondrial, CH60_HUMAN, Chaperonin, Chaperonin 60, Chaperonin, 60-KD, CPN60, fa04a05, GROEL, Heat shock 60kDa protein 1, heat shock 60kDa protein 1 (chaperonin), Heat shock protein 1 (chaperonin), Heat shock protein 60, Heat shock protein 65, heat shock protein family D (Hsp60) member 1, HLD4, Hsp 60, HSP 65, HSP-60, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, short heat shock protein 60 Hsp60s1, SPG13
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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